Since its foundation in 2006 (a decade and a half), the goal has always been to increase the added value of manufacturing companies (businesses). From the audit of businesses, through the coordination of clusters to the analysis of transport corridors, all these actions led to a focus on digitalization. (trend). The accumulated knowledge has also been embodied in spatial development programs, ecosystem development, and cooperation with leading European scientific institutions. BN aims at effective implementation of knowledge transfer catalysed by international projects and partnerships. Such cooperation ranges from the coordination of cross-border working groups (Artificial Intelligence) through the establishment of a hydrogen platform to various health industry collaborations.